Invited Speaker ICACh 2023

Sylwia Kedracka-Krok

Sylwia_Kedracka-Krok

Sylwia Kedracka-Krok

dr hab.

prof. UJ , Jagiellonian University in Kraków

Sylwia Kedracka-Krok is employed as the Associate Professor in the Department of Physical Biochemistry Faculty of Biochemistry, Biophysics and Biotechnology Jagiellonian University (Krakow, Poland) where she supervises a research group dealing with proteomic studies in neurobiology.

She graduated from the Chemistry Faculty of Jagiellonian University (Krakow, Poland) in 1995. She received her Ph.D. in biochemistry from the Department of Biochemistry, Biophysics and Biotechnology, Jagiellonian University (Krakow, Poland) in 2004 investigating the structure of regulatory proteins as well as the thermodynamics and kinetics of the interaction of these proteins with ligands and DNA using spectroscopic and microcalorimetric methods.

She developed the Proteomics and Mass Spectrometry Laboratory in Biochemistry, Biophysics and Biotechnology and in Małopolska Centre of Biochemistry JU, bringing new and advanced tools to the field of neuroscience and a wide range of other molecular and cellular topics.

Her research interests include understanding biochemical processes important in the etiopathogenesis of depression and molecular mechanisms of action of antidepressants and antipsychotic drugs using proteomic, microscopic, and functional studies.

Her research focuses on (i) characterizing the effects of selected antipsychotic drugs on the entire proteome and nuclear subproteome of rat brain tissue and cultures of human neuronal and glial cells (ii) studying the effects of silencing selected genes on the proteome of rat brain tissue (iii) studying the effects of silencing selected genes on nervous system cell phenotype, proteome, function, and response to drug treatment (iii) studying the role of human T cell subpopulations in depression.

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